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Symbol Name ID |
Elavl1
ELAV like RNA binding protein 1 MGI:1100851 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Mouse Phenotypes | immune system phenotype |
decreased B cell apoptosis |
increased T cell apoptosis |
abnormal macrophage chemotaxis |
decreased T cell proliferation |
increased susceptibility to induced colitis |
thymus hypoplasia |
abnormal thymocyte activation |
abnormal positive T cell selection |
increased double-negative T cell number |
decreased double-positive T cell number |
increased double-positive T cell number |
decreased granulocyte number |
increased granulocyte number |
decreased T-helper 17 cell number |
decreased CD4-positive, alpha-beta T cell number |
decreased CD8-positive, alpha-beta T cell number |
increased single-positive T cell number |
increased macrophage cell number |
increased monocyte cell number |
decreased leukocyte cell number |
abnormal myeloid leukocyte morphology |
abnormal spleen development |
spleen hypoplasia |
absent spleen |
abnormal B cell physiology |
abnormal T cell physiology |
increased circulating interleukin-1 beta level |
increased circulating interleukin-12 level |
increased circulating interleukin-6 level |
increased circulating tumor necrosis factor level |
lymph node hypoplasia |
decreased susceptibility to experimental autoimmune encephalomyelitis |
increased susceptibility to endotoxin shock |
decreased inflammatory response |
lung inflammation |
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| Availability | Mouse Genotype | ||||||||||||||||||||||||||||||||||||
| Elavl1tm1.1Thla/Elavl1+ | |||||||||||||||||||||||||||||||||||||
| Elavl1tm1.1Atas/Elavl1tm1.1Atas Tnfrsf4tm2(cre)Nik/Tnfrsf4+ (conditional) |
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| Elavl1tm1.1Dkon/Elavl1tm1.1Dkon Lyz2tm1(cre)Ifo/Lyz2+ (conditional) |
* | ||||||||||||||||||||||||||||||||||||
| Elavl1tm1Dkon/Elavl1tm1Dkon Edil3Tg(Sox2-cre)1Amc/Edil3+ (conditional) |
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| Elavl1tm1Dkon/Elavl1tm1Dkon Tg(Lck-cre)I57Jxm/0 (conditional) |
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| Elavl1tm1Lix/Elavl1tm1Lix Tg(Scgb1a1-rtTA)2Jaw/0 Tg(tetO-cre)1Jaw/0 (conditional) |
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| Elavl1tm1Thla/Elavl1tm1Thla Gt(ROSA)26Sortm1(cre/ERT2)Alj/Gt(ROSA)26Sor+ (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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